Recent Biological Activity of Ferulic Acid

Document Type : Narrative Review Article

Authors

1 Histology Department, Faculty of Dentistry, Sinai University, Ismailia, Egypt

2 Basic Sciences Department, Faculty of Dentistry, Sinai University, Ismailia, Egypt

Abstract

A common ingredient in fruits, drinks, and food products is 4-
hydroxycinnamic acid, which is the source of ferulic acid (FA). Scientific
evidence has shown that it has anti-inflammatory, antioxidant, and
antimicrobial properties. Its clinical use, for example, is limited to low
bioavailability and is therefore only useful in treating neurological illnesses
such as Alzheimer's disease, rapid elimination from the gastrointestinal
tract after oral treatment, and inadequate translocation across biological
barriers, such as the blood-brain barrier (BBB). Consequently, novel
nanotechnological strategies are created to control FA's intracellular
transit. This review summarizes twenty years of research on FA's
biological properties.

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